Saturday, December 5, 2009

Form 4 Chapter 2 - Cell structure & cell organisation (part 2)

here are the recap from our previous lessons .....


1) Density of organelles in specific cells:

  • example 1:
    Pancreatic cells have high density of rough ER & GA.
    because Pancreatic cells synthesise & secrete pancreatic juice (which contains enzyme) & hormone insulin.

  • example 2:
    Palisade mesophyll cells of the green leaves have high density of chloroplast organelles.
    because PMC needs to absorb sunlight during photosynthesis.
  • refer to your notes for more examples

2) Living processes of Unicellular organisms.

  • We look at 2 unicellular org. (Amoeba sp. & Paramecium sp.) to study the 8 living processes listed below.

  1. Feeding

  2. Excretion

  3. Growth

  4. Locomotion

  5. Sensitivity

  6. Respiration

  7. Reproduction

  8. Osmoregulation


  • Amoeba sp


  1. Feeding - engulf foods through a process called phagocytosis. (you should know how to explain the process, including drawing of the labelled diagrams)







  2. Locomotion - forming of pseudopodia through cytoplasmic projection.
  3. Osmoregulation - carried out by contractile vacuole. (you shld know the explanation here)
  4. Reproduction - only asexual reproduction - binary fission. (you should also know the drawing of labelled diagrams). spore formation.











  • Paramecium sp





  1. Feeding - beating the cilia to bring food particles to its oral groove, into the gullet & cytostome.
  2. Locomotion - swimming through beating of cilia.
  3. Osmoregulation - carried out by the 2 contractile vacuole. explanation....













  4. Reproduction
  • asexual reproduction - binary fission
  • sexual reproduction - conjugation, where exchange of genetic materials occurs between 2 parameciums.







I look forward to meet you again in the next lesson. take care.

Wednesday, December 2, 2009

World AIDS Day - 1st December



World AIDS Day serves many purposes, among others is raising AWARENESS.

HIV/AIDS is a global issue! here are some statistic we need to know:
  • 33 million people living with HIV/AIDS globally
  • 2.7 million people are diagnosed with HIV infections every year (new cases!)
  • 2 million people die every year around the world from HIV/AIDS



What is HIV?







        Diagram shows a HIV virus


                            1. HIV stands for human immunodeficiency virus (HIV). The virus infects and gradually destroys immune system cells, reducing the body's protection against infection and cancers. A person infected with HIV is infected for life - there's no cure.
                            2. Over time, as the immune system weakens, a person with HIV may develop rare infections or cancers. When these are particularly serious, the person is said to have acquired immune deficiency syndrome (AIDS).

                            Causes and risk factors

                            1. HIV can only be passed on if infected blood, semen, vaginal fluids or breast milk get inside another person's body.
                            2. The two main ways in which a person can become infected are:
                            • Vaginal or anal sexual intercourse (without a condom) with an infected person.
                            • Using a needle or syringe that's already been used by someone who's infected.

                              * An infected pregnant woman can also pass the virus to her unborn baby, before or during the birth, or through breastfeeding. Improved treatment and care for women with HIV means far fewer children are now born with HIV.

                              *Other potential routes of transmission include: read more at HIV/AIDS - BBC Health

                            Symptoms

                            • There are no immediate signs or symptoms after infection. Research has shown that after a few weeks some people experience flu-like symptoms, but these usually go undiagnosed. The only way to know if you have HIV is to be tested.
                            • The test looks for HIV antibodies in the blood. It takes three months for antibodies to develop, so if you test soon after possible infection the result may be inaccurate. A second test at 12 weeks after possible risk to the virus will give you a conclusive result.


                            Treatment and recovery

                            • There's no cure for HIV, but there are drugs called antiretrovirals that can help prevent someone infected with HIV from becoming ill.
                            • These drugs can significantly increase the life expectancy of someone with HIV, but the drugs must be taken every day for life, otherwise the treatment will stop being effective and the person affected may become ill.
                            Symptoms of AIDS





                            Click the appropriate links below to learn more about HIV & AIDS:

                            1) AIDS epidemic today - watch the video - click here

                            2) 100 stories on HIV & AIDS

                            3) Walk in AIDS patients' shoes - click here .

                            ..Editor's note: On his current tour, R&B singer Maxwell is highlighting the impact of antiretroviral medication in fighting HIV-AIDS.

                            4) HIV vaccine brings new hope (a breakthrough)- watch the video - click here.

                            5) Get involved: Fight HIV & AIDS


                            6) Click on the related links at the right panel of this blog.

                            Thursday, November 12, 2009

                            Form 5 Chapter 1 - Transport (Part 2)






                            1. The third component in circulatory system is the Heart.

                            2. The Human Heart;

                            • made up of myogenic cardiac muscles.
                            • has 4 chambers; 2 atria, 2 ventricles.
                            • you should know: the flow of blood through the heart - refer your notes
                            • questions:
                              Why does the letf ventricle has thicker & muscular wall than the right ventricle?
                              What is meant by myogenic?
                              What are the 2 systems that can control the human heartbeat?
                            • Circulation of blood is made possible by:
                              1) pumping of the heart;
                              2) contractions of skeletal muscles around the veins.

                            3. Pumping of the Heart:

                            • One cardiac cycle consists of 2 stages/phases: diastole & systole.
                            • Sino-atrial node (SA node) is the pacemaker of the heart - it initiates & coordinates heartbeat.
                            • SA node generates electrical impulses which causes both atria to contract.
                            • Atrio-ventricular node (AV node) receive the electrical impulses .... & causes both ventricles to contract at the same time.
                            • Artificial pacemaker helps to maintain adequate heartbeat//regulate heart rhythm in heart patient.

                            4. The negative feedback regulation of blood pressure -> refer your diagram.

                            • the receptors? baroreceptors located at the wall of the arch of aorta & carotid arteries.
                            • the effectors? Heart muscles & smooth muscles of blood vessels.

                            5. The circulatory system in insects, fish, amphibians & humans.

                            • you should know how to describe the type of circulation. (remember to follow the numbering & tell your story)
                              1) Open circulatory system (in grasshopper)
                              2) Single closed circulatory system (in fish)
                              3) Incomplete double closed circulatory system. (in frogs)
                              4) Complete double closed circulatory system. (in humans)
                            • questions:
                              1) what is an open system? haemolymph (circulating blood-like fluid) is pumped into open vessels in a non-continuous circuit around the body//is pumped directly into the body cavity of the organism
                              2) what is a closed system? Blood is pumped into blood vessels & flows through closed vessels in a continuous circuit around the body.
                              3) What is meant by double closed circulatory system?
                              4) What is meant by incomplete?

                            6. Blood clotting mechanism -> refer to your diagram.

                            • you shld know these terms:
                              1) thrombosis, the formation of thrombus
                              2) embolus & embolism
                              3) Heart attack (MI), chest pain (angina)
                              4) Haemophilia
                              5) Coronary artery bypass surgery to treat blocked/narrowed coronary arteries. click to read more.

                            Should you hv any questions regarding the above, ask me during our weekly meeting.

                            take care.

                            to view animated heart, click here.

                            Form 4 Chapter 2 - Cell structure & cell organisation (Part 1)

                            Dear students,

                            I know this week's lesson was quite heavy for most of you. Below are what we have learned & I hope i won't be writing this long in my next posting unless necessary.

                            1. Experiment: to observe the structures of plant cells & animal cells with a light microscope. (plant cells: onion & Hydrilla sp. & Elodea sp. epidermal cell; animal cells: Human cheek epidermal cells)
                            *under the light microscope, you are able to observe cell wall, plasma membrane, cytoplasm, nucleus, and sometime chloroplast.
                            a) similarities btw plant cell & animal cell : nucleus, cytoplasm, plasma membrane
                            b) In plant cell, there is cell wall, large/big central vacuole, chloroplasts (in photosynthetic cells)
                            c) In human/animal cells, there is no CW, No chloroplasts, usually vacuole not present.

                            2. Cellular components
                            A) which are not organelles:
                            i) Cell Wall (CW): (plant cell only)
                            *characteristics: rigid cellulose outer layer, permeable to all fluid.
                            *fn: protection, support, maintain shape of plant cell, prevent cells from bursting.

                            ii) Plasma membrane (PM):
                            *characteristics: composed of 2 lipid layers (phospholipids & proteins),thin flexible layer, semi-permeable.
                            * fn: controls/regulates the movements of substances entering & leaving the cell,separate the cell from its environment, allow exchange of substances.

                            iii) Cytoplasm:
                            *characteristic: jelly-liked substances, contains salts, dissolved gases, nutrients, enzymes, organic & inorganic substances. 70-90% are water. with organelles suspended in it.
                            *fn: medium for biochemical reactions & cellular metabolism.

                            An illustrated animal cell as seen under the electron microscope.


                            An illustrated plant cell as seen under the electron microscope.



                            B) Cellular components which are ORGANELLES:
                            *what are organelles?
                            ->organelles are cellular components the can perform specific functions/specialised functions within the cell. Many are enclosed by membrane.

                            1) Nucleus:
                            * largest organelle.
                            * bounded by nuclear membrane - double membrane with pores.
                            * contains chromatin (DNA - Deoxyribonucleic Acid)
                            * chromatin? chromosome?
                            * has nucleolus - nucleolus makes RNA which is needed to make ribosomes. (ribosomes are produced by nucleolus)
                            #fn: direct & control all the activities of the cell.

                            2) Vacuole:
                            *small cavity contains cell sap & is enclosed by tonoplast (a SPM)
                            #fn: for storage, digestion & waste removal,

                            3) Ribosomes: (non-membrane bound particles)
                            * compact, spherical organelles, consists of RNA (Ribonucleic Acid) & proteins.
                            * either attached to rough ER or suspended freely in the cytoplasm.
                            #fn: sites of protein synthesis.

                            4) Endoplasmic reticulum (ER):
                            * a system of flattened, membrane-bound sacs in the form of tubes & sheets.
                            * interconnected to nuclear membrane.
                            *form an extensive transport system in the cell.
                            * exists as Rough ER & Smooth ER

                            i) Rough ER:
                            * flat sealed sac which is continuous with the outer nuclear membrane, outer surface is covered with ribosomes that give it a rough appearance.
                            # fn: transport proteins made by ribosomes throughout the cell

                            ii) Smooth ER:
                            * tubular sealed sac - either extend from the rough ER or extend separately.
                            * does not have ribosomes
                            # fn: synthesis lipids & steroids hormone, breakdown of lipid-soluble toxins in liver cells,

                            5) Golgi apparatus/Golgi body/Golgi complex: (GA)
                            * a stack of flattened, membrane-bound sacs having form continuously at one end of the stack & budded off as vesicles at the other end.
                            #fn: as a processing, modification, packaging & transport centre of carbohydrate, proteins & glycoproteins. (site of Enzyme production & lysosome formation)

                            6) Mitochondrion: Mitochondria (plural)





                            * spherical to rod-shaped organelles with double membrane.
                            * inner membrane folded inwards to form projections called the cristae (crista - singular)
                            #fn: site for cellular respiration ('powerhouse' of the cell) to produce/generate/release energy (ATP- Adenosine Triphosphate).

                            7) Lysosomes:
                            * membrane-bound spherical vesicle formed by pinching-off from GA.
                            *contains digestive enzymes
                            #fn: as digestive compartment of the cell (intracellular digestion)
                            breaking down food, example in Amoeba sp.
                            breaking down unwanted structure/molecules, example worn-out/old organelles, whole cell, old Red Blood Cell.
                            (common in animal cell, uncommon in plant cell because digestive enzymes are found in the vacuole)


                            8) Centrioles: (only found in animal cells)
                            * pairs of cylindrical organelles located outside/near the nucleus.
                            * made up of microtubules.
                            #fn: form spindle fibres during cell division, synthesise cilia & flagella in Unicellular organism.

                            9) Chloroplast: (only found in photosynthetic plant cells)




                            * lens-shaped organelle with double membrane.
                            *contains green pigment - chlorophyll
                            #fn: chlorophyll trap light energy & converts light E into chemical E during PS.
                            (diagram -- remember the stack of little round flat pillow? one stack is called granum, grana (plural))


                            3)Comparison btw the structure in animal cell & plant cell.
                            - refer to your table.
                            *****************
                            Homework:
                            1) Do structure question 1 + 2 (Page 3)
                            2) State 2 similarities btw mitochondrion & chloroplast.
                            3) Compare a plant cell & human white blood cell.
                            4) What is chromosome?
                            5) You need to practise drawing & labelling a mitochondrion & chloroplast organelle in 2D image (not 3D). just like what i have drawn in the class.
                            *****************

                            see you in the next lesson.

                            teacher sharon
                            13th Nov 2009

                            Tuesday, November 10, 2009

                            Form 5 Chapter 1 - Transport (Part 1)

                            Dear students,
                            Let's recap what we have learned in the last lesson.

                            We learned:
                            1) Why big size organism/large multicellular organism like human needs a transport system while small size organism(unicellular organism) eg: Amoeba sp. doesn't need a transport system.
                            This can be demonstrated through an experiment-- refer yr handout. How the size of an organism affect its TSA/V ratio, and how this affect the rate of diffusion.
                            I hope you can find time to do the experiment at home, or else you can do it at the lab. next year.

                            2) We learned the 3 components of blood circulatory system. ie: the Heart, Blood vessels & blood.
                            a) We also learn about blood composition. Whole blood consists of blood plasma & blood cells (eg: RBC, WBC & platelets). their structure, functions, others.
                            b) you shld know how RBC adapts to carry out its function efficiently. (10 marks)
                            c) the differences in structure & function btw RBC & WBC. btw granulocyte & agranulocyte.

                            d) blood vessels: Arteries, arterioles, blood cap., venules, veins.
                            i) how are they differ? & their function & structure. (refer yr notes for comparison)
                            ii) drawing the cross-section of an artery, b/cap, veins.
                            iii) why artery has thicker wall than vein, etc
                            iv) one colourful diagram for you to refer to.




                            Let me know if you need further explanation on the above; of course during our weekly meeting.
                            See you again in the next lesson.

                            Rgds,
                            teacher sharon

                            Friday, October 23, 2009

                            Not Exactly Rocket Science - a resourceful & interesting site!

                            I like this site.
                            If you want to keep abreast of the latest science issues/development, remember to visit this site - Not Exactly Rocket Science by Ed Yong - an award winning science writer.

                            "One of the best sites for in-depth analysis of interesting scientific papers"
                            - The Times

                            ps: i have also made a link at the bottom right panel.

                            Tuesday, October 20, 2009

                            Education in Malaysia

                            Dear students, i find this website quite interesting to read on because it is about education, about you & me & our beloved country, & our future as a nation. The website highlights many relevant & important issues which are closer to home.

                            Click here or go to Choose Your Link & click on the link (at bottom, right side panel).

                            Friday, October 16, 2009

                            Greenhouse effect & global warming (3)




                            In this posting, i would like to introduce a new term to you. It is called Carbon Footprint.. Some of you might have already heard
                            of this term because it was introduced sometime ago. And we shall see how we can help to reduce our carbon footprint. Pls note that this is not part of your biology SPM syllabus, but believe me, it is worth learning.

                            According to wikipedia, A carbon footprint is "the total set of greenhouse gas (GHG) emissions caused directly and indirectly by an individual, organization, event or product". For simplicity of reporting, it is often expressed in terms of the amount of carbon dioxide, or its equivalent of other GHGs, emitted.

                            Each one of us contributes to GHGs emission everyday while going about doing our daily activity which cause climate change/global warming. So, what is your carbon footprint? click on this calculator to find out yourself.

                            After doing the above exercise, i realised that my carbon footprint is above average, i better do something to reduce my carbon footprint.




                            What should/can we do?

                            1. Turn it off when not in use (fans, lights, television, DVD player, Hi Fi, computer, playstation, etc. etc. ...) click here to learn more.
                            2. Fill the kettle with only as much water as you need
                            3. Do your weekly shopping in a single trip
                            4. Hang out the washing/clothes to dry rather than tumble drying it in the machine
                            5. Sign up to a green energy supplier, who will supply electricity from renewable sources (e.g. wind and hydroelectric power) - this will reduce your carbon footprint contribution from electricity to zero
                            (*unfortunately, we can't do this because Energy Supply in Malaysia is monopoly by only one company called Tenaga Nasional Berhad.... bad luck )
                            6. Fit energy saving light bulbs - (*i know the bulb is a bit costly, but try to encourage your parents to purchase, i believe you can explain the benefits - it is long-lasting & save energy in the long run!)
                            7. Replace your old fridge / freezer (if it is over 15 years old), with a new one with energy efficiency rating of "A"
                            8. Replace your old boiler with a new energy efficient condensing boiler
                            9. Car pool to school/tuition centres
                            10. Use public transport - bus or train rather car. (*Unfortunately in Malaysia, this is a big problem! bad public transport, the bus either late or never arrived! or packed like sardine?)
                            11. For short journeys either walk or cycle (eg: to the school, shop, to your friend's house doing revision/homework/project, to tuition)
                            12. Use biodiesel fuel (*unfortunately, only for diesel engine vehicle) click here to know more.
                            13. Don't buy bottled water if your tap water is safe to drink. (*Don't do this if you live in Malaysia!!! always boil your water.)
                            14. Buy local fruit and vegetables, or even try growing your own
                            15. Buy foods that are in season locally
                            16. Don't buy fresh fruit and vegetables which are out of season, they may have been flown in
                            17. Reduce your consumption of meat (*because farm animals contribute to more GHGs emission)
                            18. Try to only buy products made close to home (look out and avoid items that are made in the distant lands) - (* i know this is not easy because we Malaysian like to buy imported foods/fruits, or maybe our local products are less attractive)
                            19. Buy organic produce (*not easy to do this because they are not cheap!)
                            20. Don't buy over packaged products. (*did you notice that some items/products have many-many-many layers of packaging materials??)
                            21. Recycle as much as possible.
                            22. For those who are rich, cut down your visit to Saunas, Health clubs, restaurants, go-karting etc. etc... (these places contribute to more GHGs emission.)

                            (the above list has been modified from carbon footprint. click here for the full list)

                            I hope we can try to do some of the activities listed above if not all.
                            Together we can fight global warming!


                            For more carbon footprint cartoons, click here.

                            Wednesday, October 14, 2009

                            Greenhouse effect & global warming (2)

                            Carbon emission.

                            I hope you have read my posting about the above which i posted sometime last month.

                            A few weeks ago during our biology lesson about carbon emission, we have discussed some possible ways we could help to reduce/minimise the release of carbon dioxide. I have suggested that maybe we could try to use less air-cond at home (eg: use the fan at night), or plant a small tree, etc. I hope some of you have tried those ideas, because i have.

                            Once i was so excited upon hearing the arrival of a hybrid car (toyota prius) to the M'sia market - sometime in August this year. But after checking further, i realise that it is really way too costly to own one due to high taxes imposed by our government, which come to RM175,000 for a 1.8L! OMG, the price is doubled compared to my family car! To be honest, i love this car but i can't afford.
                            I wonder why the government make it so discouraging/difficult for us to own a greener car to save the environment! Are they not worry about pollution/global warming? or are they trying to protect the proton? If it is the proton issue, those engineers at proton you better work harder & come out with your own hybrid version that WORKS!

                            Let's move on.....

                            I found this informative video at TED about global warming.

                            Al Gore presents updated slides from around the globe to make the case that worrying climate trends are even worse than scientists predicted, and to make clear his stance on "clean coal."
                            Al Gore mentions about the melting ice caps, click here to view.




                            If you want to know how a hybrid car works, click here. look for prius-intelligent.

                            (note: i don't have any stake in toyota)

                            Thursday, October 8, 2009

                            Bone marrow transplant - how they do it?

                            Some of you have asked me how to harvest bone marrow from a donor.
                            I would like to share this link with you, hope you get some idea.

                            Daniel Kraft demos his Marrow Miner -- a new device that quickly harvests life-saving bone marrow with minimal pain to the donor. He emphasizes that the adult stem cells found in bone marrow can be used to treat many terminal conditions, from Parkinson's to heart disease.click here.